Cold Fusion EX LG Sciences Review

Cold Fusion EX increases strength, stamina and size. We do this by combining a unique ratio of ingredients that are proven in the scientific studies to perform a unique function. These combined are why LG Sciences Cold Fusion is up to SIX times better than standard creatine. This article is heavy on the science, but rest assured that this means that you are getting the best quality product with the heavy science to back it up. Seth (my scientist) wrote the technical stuff, I will translate for us “less science minded”

Creatine Ethyl Ester: Creatine ethyl ester is one of the newest forms of creatine. The ethyl ester prevents breakdown in the gut and prolongs the life of creatine in the blood. Combined with creatine monohydrate this results in a one-two punch of fast acting immediate action coupled with the longer duration of creatine ethyl ester. – CEE gives you a longer acting creatine, the right amount works, too much and it tastes like battery acid.

Creatine Monohydrate: The granddaddy of all creatine. Creatine monohydrate has been proven time and time again in the scientific literature to not only increase stamina and strength but also to cause skeletal muscle growth through hypertrophy (expansion of existing muscle cells) and hyperplasia (the creation of new muscle cells from stem cells). Creatine loads water and nutrients into muscle cells resulting in massive pumps and an enhanced anabolic state. – Nothing works like Creatine Monohydrate, it is proven and is shown to increase the forming of new muscle cells. We use 200mesh pharmaceutical grade.

Creatine Malate: Creatine bonded to the tricarboxylic acid cycle intermediate, L-Malate. L-Malate plays a critical role in shuttling NADH, an energy molecule, from the cytoplasm into the mitochondria for energy production. This results in an increase in physical stamina and a reduction in skeletal muscle damage (1). – Malate’s increase the energy production of creatine, giving you increased stamina.

Taurine: Taurine is part of the native defense mechanism against oxidative damage in skeletal muscle (2). Taurine is also a modulator of contractile function in mammalian skeletal muscle and increases the force responses by augmenting calcium accumulation and release (3). – Taurine gives you extra energy and pumps.

L-Leucine: Leucine has been shown to not only reduce the rate of protein degradation in skeletal muscle as a result of resistance training but to also increase protein accumulation and strength (4). – Leucine is the first amino acid used up when you work out. It is proven to be anabolic.

Beta Alanine: Beta Alanine is an amino acid that is a component of carnosine. Stuides have shown that beta alanine supercharges the effects of creatine, resulting in greater lean mass gains and strength increases (5). – Beta Alanine buffers lactic acid and gives you longer workout times and reduces failure.

Aspartic Acid: Aspartic acid plays a major role in the malate-aspartate shuttle and acts to recharge L-Malate. Supplementation with aspartic acid has resulted in increased endurance and decreased lactic acid buildup. Furthermore, studies show decreased rate of glycogen depletion during exercise due to increased utilization of free fatty acids over glycogen (6,7) – Aspartic Acid increases endurance and performance.

Yohimbine HCL: Yohimbine is an alpha-adrenergic antagonist. Supplementation with yohimbine results in augmentation of nitric oxide synthesis and increased vasodilation – which means more blood, water and nutrients delivered to your muscles. – Yohimbine gives you the mental lift in the gym, without the crash of caffeine. It also increases blood flow, making NO work better.

L-Arginine: L-Arginine is THE precursor to nitric oxide (NO) production. Nitric oxide is the major vasodilator in blood vessels. Vasodilation causes blood vessels to open up, allowing more blood to flow. This gives you the massive pumps that you experience when supplementing with arginine. This pump not only looks great but it also helps to build muscle by delivering more nutrients where you need it most. – Arginine is the base for a good NO pump, we prefer a mix of many types to get the maximum benefit.

Arginine AKG: Arginine bound to the tricarboxylic acid intermediate, alpha-ketoglutate. Alpha-ketoglutarate is important for driving the malate-aspartate shuttle and is one of the most important nitrogen transporters. In addition, alpha-ketoglutarate is a precursor to the neurotransmitters glutamate and GABA. – Arginine AKG is a good form of Arginine proven to help build strength and give pumps.

Arginine Orotate: Arginine bound to orotic acid results in a longer duration of action and improved absorption of arginine. – Another form of Arginine that lasts longer in the body.

Mormordica: Momordica is an herbal ingredient that has been used in China for over a thousand years. Momordica upregulates the expression of GLUT-4, the primary glucose transporter in skeletal muscle. This results in increased glucose and protein transport into muscle. This increased flow of nutrients also loads creatine and water into the muscle (8,9). – This stuff is really cool, it shuttles all the other stuff into the muscle. Unlike inferior products (like ALA) it pushes both amino acids and sugar into the muscle (all the above stuff are amino acids, which is why Cold Fusion works better than anything else).

Pomegranate Powder: Pomegranate juice contains potent antioxidants that protect nitric oxide (NO) from oxidative destruction. This results in an increase in the activity of NO as well as the duration of action (10). – Pomegranate is good for you in many ways, but it is shown to increase your pumps by extending the life of NO.

Spirulina: Spirulina has been shown to decrease oxidative damage in skeletal muscle but it also has another interesting effect. Spirulina augments the vasodilating effect of nitric oxide while at the same time, decreasing vasoconstriction by reducing the synthesis and release of vasoconstricting eicosanoids (11). – Spirulina is known as an energy food that increases pumps and reduces muscular fatigue.

This unique combination of ingredients will give you the biggest pumps during your workouts while at the same time producing the optimal anabolic state. Hopefully, our dual explanations give you science guys and normal dudes a chance to see why Cold Fusion EX is so great. Oh, you have to taste it! It is freaking amazing.

References

1. Wu J, Wu Q, Huang J, Chen R, Cai M, Tan J. Effects of L-malate on physical stamina and activities of enzymes related to the malate-aspartate shuttle in liver of mice. Physiol Res. 2006 Mar 23

2. Kingston R, Kearns S, Kelly C, Murray P. Effects of systemic and regional taurine on skeletal muscle function following ischaemia-reperfusion injury. J Orthop Res. Mar;23(2):310-4, 2005

3. Bakker AJ, Berg HM. Effect of taurine on sarcoplasmic reticulum function and force in skinned fast-twitch skeletal muscle fibres of the rat. J Physiol. Jan 1;538(Pt 1):185-94, 2002

4. Coburn JW, Housh DJ, Housh TJ, Malek MH, Beck TW, Cramer JT, Johnson GO, Donlin PE. Effects of leucine and whey protein supplementation during eight weeks of unilateral resistance training. J Strength Cond Res. May;20(2):284-91, 2006

5. Hoffman J, Ratamess N, Kang J, Mangine G, Faigenbaum A, Stout J. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes. Int J Sport Nutr Exerc Metab. Aug;16(4):430-46, 2006

6. Marquezi ML, Roschel HA, dos Santa Costa A, Sawada LA, Lancha AH Jr. Effect of aspartate and asparagine supplementation on fatigue determinants in intense exercise. Int J Sport Nutr Exerc Metab. Mar;13(1):65-75, 2003

7. Lancha AH Jr, Recco MB, Abdalla DS, Curi R. Effect of aspartate, asparagine, and carnitine supplementation in the diet on metabolism of skeletal muscle during a moderate exercise. Physiol Behav. Feb;57(2):367-71, 1995

8. Cummings E, Hundal HS, Wackerhage H, Hope M, Belle M, Adeghate E, Singh J. Momordica charantia fruit juice stimulates glucose and amino acid uptakes in L6 myotubes. Mol Cell Biochem. Jun;261(1-2):99-104, 2004

9. McCarty MF. Does bitter melon contain an activator of AMP-activated kinase? Med Hypotheses. 63(2):340-3, 2004

10. Ignarro LJ, Byrns RE, Sumi D, de Nigris F, Napoli C. Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide. Nitric Oxide. Sep;15(2):93-102, 2006

11. Paredes-Carbajal MC, Torres-Duran PV, Diaz-Zagoya JC, Mascher D, Juarez-Oropeza MA. Effects of dietary Spirulina maxima on endothelium dependent vasomotor responses of rat aortic rings. Life Sci. 61(15):PL 211-9, 1997